{"product_id":"rheumocam-1-5mg-ml-42-ml-meloxicam-dogs","title":"RHEUMOCAM 1.5MG\/ML - 42 ML \/\/ Meloxicam \/\/ dogs","description":"\u003ch2 class=\"product-content__block-heading\"\u003e\u003cspan dir=\"auto\"\u003eDescription\u003c\/span\u003e\u003c\/h2\u003e\n\u003cdiv\u003e\n\u003ch1\u003e\u003cspan dir=\"auto\"\u003eRheumocam 1.5 mg\/ml, oral suspension for dogs\u003c\/span\u003e\u003c\/h1\u003e\n\u003cp\u003e\u003cstrong\u003e\u003cspan dir=\"auto\"\u003eQUALITATIVE AND QUANTITATIVE COMPOSITION\u003c\/span\u003e\u003c\/strong\u003e\u003cbr\u003e\u003cspan dir=\"auto\"\u003eOne ml contains:\u003c\/span\u003e\u003cbr\u003e\u003cspan dir=\"auto\"\u003eActive substance: Meloxicam 1.5 mg\u003c\/span\u003e\u003cbr\u003e\u003cspan dir=\"auto\"\u003eExcipient: Sodium benzoate 5 mg.\u003c\/span\u003e\u003cbr\u003e\u003cstrong\u003e\u003c\/strong\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003e\u003cspan dir=\"auto\"\u003ePHARMACEUTICAL FORM \u003c\/span\u003e\u003c\/strong\u003e\u003cspan dir=\"auto\"\u003e\u003cspan\u003e \u003c\/span\u003eOral suspension.\u003c\/span\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003e\u003cspan dir=\"auto\"\u003eTarget species:\u003c\/span\u003e\u003c\/strong\u003e\u003cspan dir=\"auto\"\u003e\u003cspan\u003e \u003c\/span\u003eDogs.\u003c\/span\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003e\u003cspan dir=\"auto\"\u003eIndications for use, specifying the target species\u003c\/span\u003e\u003c\/strong\u003e\u003cbr\u003e\u003cspan dir=\"auto\"\u003eAlleviation of inflammation and pain in acute and chronic musculoskeletal disorders in dogs.\u003c\/span\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003e\u003cspan dir=\"auto\"\u003eContraindications\u003c\/span\u003e\u003c\/strong\u003e\u003cbr\u003e\u003cspan dir=\"auto\"\u003eDo not use in pregnant or lactating animals.\u003c\/span\u003e\u003cbr\u003e\u003cspan dir=\"auto\"\u003eDo not use in animals suffering from gastrointestinal disorders such as irritation and bleeding, liver, heart or kidney disease or bleeding disorders.\u003c\/span\u003e\u003cbr\u003e\u003cspan dir=\"auto\"\u003eDo not use in case of hypersensitivity to the active substance or to any of the excipients.\u003c\/span\u003e\u003cbr\u003e\u003cspan dir=\"auto\"\u003eDo not use in dogs less than 6 weeks of age.\u003c\/span\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003e\u003cspan dir=\"auto\"\u003eSpecial warnings\u003c\/span\u003e\u003c\/strong\u003e\u003cbr\u003e\u003cspan dir=\"auto\"\u003eNone.\u003c\/span\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003e\u003cspan dir=\"auto\"\u003eSpecial precautions for use\u003c\/span\u003e\u003c\/strong\u003e\u003cbr\u003e\u003cspan dir=\"auto\"\u003eUse in animals that are dehydrated, hypovolemic or hypotensive should be avoided as this carries a potential risk of increased renal toxicity.\u003c\/span\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003e\u003cspan dir=\"auto\"\u003eSpecial precautions to be taken by the person administering the veterinary medicinal product to animals\u003c\/span\u003e\u003c\/strong\u003e\u003cspan dir=\"auto\"\u003e\u003cspan\u003e \u003c\/span\u003e:\u003c\/span\u003e\u003cbr\u003e\u003cspan dir=\"auto\"\u003ePeople with known hypersensitivity to non-steroidal anti-inflammatory drugs (NSAIDs) should avoid contact with the veterinary medicinal product.\u003c\/span\u003e\u003cbr\u003e\u003cspan dir=\"auto\"\u003eIn case of accidental ingestion, seek medical advice immediately and show the package leaflet or the label to the physician.\u003c\/span\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003e\u003cspan dir=\"auto\"\u003eAdverse reactions (frequency and seriousness)\u003c\/span\u003e\u003c\/strong\u003e\u003cbr\u003e\u003cspan dir=\"auto\"\u003eTypical adverse reactions associated with NSAIDs such as loss of appetite, vomiting, diarrhoea, occult gastrointestinal bleeding, lethargy and renal failure have been reported occasionally. In very rare cases, haemorrhagic diarrhoea, haematemesis, gastrointestinal ulceration and elevated liver enzymes have been reported.\u003c\/span\u003e\u003cbr\u003e\u003cspan dir=\"auto\"\u003eThese adverse reactions generally occur within the first week of treatment and are in most cases transient in nature, disappearing after the end of treatment, however, in very rare cases they may be severe or fatal.\u003c\/span\u003e\u003cbr\u003e\u003cspan dir=\"auto\"\u003eIf adverse reactions occur, treatment should be discontinued and the advice of a veterinary surgeon should be sought.\u003c\/span\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003e\u003cspan dir=\"auto\"\u003eUse during pregnancy, lactation or lay\u003c\/span\u003e\u003c\/strong\u003e\u003cbr\u003e\u003cspan dir=\"auto\"\u003eThe safety of the veterinary medicinal product has not been established during pregnancy and lactation.\u003c\/span\u003e\u003cbr\u003e\u003cspan dir=\"auto\"\u003eInteractions with other medicinal products or other forms of interaction\u003c\/span\u003e\u003cbr\u003e\u003cspan dir=\"auto\"\u003eOther NSAIDs, diuretics, anticoagulants, aminoglycoside antibiotics and substances with a high level of protein binding may compete with protein binding, thus leading to toxic effects. Rheumocam should not be administered together with other NSAIDs or glucocorticosteroids.\u003c\/span\u003e\u003cbr\u003e\u003cspan dir=\"auto\"\u003ePrevious treatment with anti-inflammatory substances may lead to additional or increased adverse effects, therefore it is advisable that treatment with such veterinary medicinal products be discontinued at least 24 hours before starting treatment. On the other hand, the establishment of the withdrawal period should be made taking into account the pharmacological properties of the veterinary medicinal products previously used.\u003c\/span\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003e\u003cspan dir=\"auto\"\u003eAmounts to be administered and route of administration\u003c\/span\u003e\u003c\/strong\u003e\u003cbr\u003e\u003cspan dir=\"auto\"\u003eShake well before use.\u003c\/span\u003e\u003cbr\u003e\u003cspan dir=\"auto\"\u003eAdminister mixed with food.\u003c\/span\u003e\u003cbr\u003e\u003cspan dir=\"auto\"\u003eInitial treatment is a single dose of 0.2 mg meloxicam\/kg body weight on the first day. Treatment will be continued by oral administration once daily (at 24-hour intervals) with a maintenance dose of 0.1 mg meloxicam\/kg body weight. Particular care must be taken to ensure accuracy of dosing. The suspension can be administered using the Rheumocam measuring syringe provided in the package.\u003c\/span\u003e\u003cbr\u003e\u003cspan dir=\"auto\"\u003eThe syringe is adaptable to the dropper of the bottle and has a scale graduated in kg body weight corresponding to the maintenance dose (i.e. 0.1 mg meloxicam\/kg body weight).\u003c\/span\u003e\u003cbr\u003e\u003cspan dir=\"auto\"\u003eVolume to be administered according to the dog's weight:\u003c\/span\u003e\u003cbr\u003e\u003cstrong\u003e\u003cspan dir=\"auto\"\u003eBody weight (kg) Maintenance dose (ml)\u003c\/span\u003e\u003cbr\u003e\u003cspan dir=\"auto\"\u003e                  7.5 0.5\u003c\/span\u003e\u003cbr\u003e\u003cspan dir=\"auto\"\u003e                  15 1\u003c\/span\u003e\u003cbr\u003e\u003cspan dir=\"auto\"\u003e                  22.5 1.5\u003c\/span\u003e\u003cbr\u003e\u003cspan dir=\"auto\"\u003e                  30 2\u003c\/span\u003e\u003cbr\u003e\u003cspan dir=\"auto\"\u003e                  37.5 2.5\u003c\/span\u003e\u003cbr\u003e\u003cspan dir=\"auto\"\u003e                  45 3\u003c\/span\u003e\u003cbr\u003e\u003cspan dir=\"auto\"\u003e                  52.5 3.5\u003c\/span\u003e\u003cbr\u003e\u003cspan dir=\"auto\"\u003e                  60 4                  \u003c\/span\u003e\u003c\/strong\u003e\u003c\/p\u003e\n\u003cp\u003e \u003c\/p\u003e\n\u003cp\u003e\u003cspan dir=\"auto\"\u003eThus, for the initiation of treatment on the first day, a volume twice that of the maintenance dose will be required.\u003c\/span\u003e\u003cbr\u003e\u003cspan dir=\"auto\"\u003eClinical response normally occurs within 3 to 4 days. If no clinical improvement occurs, treatment should be discontinued after a maximum of 10 days.\u003c\/span\u003e\u003cbr\u003e\u003cspan dir=\"auto\"\u003eOverdose (symptoms, emergency procedures, antidotes), as appropriate\u003c\/span\u003e\u003cbr\u003e\u003cspan dir=\"auto\"\u003eIn case of overdose, symptomatic treatment should be initiated.\u003c\/span\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003e\u003cspan dir=\"auto\"\u003eWaiting time\u003c\/span\u003e\u003c\/strong\u003e\u003cbr\u003e\u003cspan dir=\"auto\"\u003eNot applicable.\u003c\/span\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003e\u003cspan dir=\"auto\"\u003ePHARMACOLOGICAL PROPERTIES\u003c\/span\u003e\u003c\/strong\u003e\u003cbr\u003e\u003cspan dir=\"auto\"\u003ePharmacotherapeutic group: Non-steroidal anti-inflammatory and antirheumatic products (oxicams).\u003c\/span\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003e\u003cspan dir=\"auto\"\u003ePharmacodynamic properties\u003c\/span\u003e\u003c\/strong\u003e\u003cbr\u003e\u003cspan dir=\"auto\"\u003eMeloxicam is a non-steroidal anti-inflammatory drug (NSAID) of the oxicam class, which acts by inhibiting prostaglandin synthesis, thus exerting anti-inflammatory, analgesic, antiexudative and antipyretic effects. It reduces leukocyte infiltration into inflamed tissue. It also, to a lesser extent, inhibits collagen-induced platelet aggregation. In vitro and in\u003c\/span\u003e\u003cbr\u003e\u003cspan dir=\"auto\"\u003evivo studies have demonstrated that meloxicam exerts a stronger inhibitory effect on cyclooxygenase-2 (COX-2) than on cyclooxygenase-1 (COX-1).\u003c\/span\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003e\u003cspan dir=\"auto\"\u003ePharmacokinetic properties\u003c\/span\u003e\u003c\/strong\u003e\u003cbr\u003e\u003cstrong\u003e\u003cspan dir=\"auto\"\u003eAbsorption\u003c\/span\u003e\u003c\/strong\u003e\u003cbr\u003e\u003cspan dir=\"auto\"\u003eMeloxicam is completely absorbed after oral administration, and peak plasma concentrations are achieved after approximately 7.5 hours. If the product is used according to the recommended dosage regimen, stable plasma concentrations of meloxicam are reached on the second day of treatment.\u003c\/span\u003e\u003cbr\u003e\u003cstrong\u003e\u003cspan dir=\"auto\"\u003eDistribution\u003c\/span\u003e\u003c\/strong\u003e\u003cbr\u003e\u003cspan dir=\"auto\"\u003eWithin the therapeutic dose range, there is a linear relationship between the administered dose and the plasma concentration obtained. Approximately 97% of the amount of meloxicam binds to plasma proteins. The volume of distribution is 0.3 l\/kg.\u003c\/span\u003e\u003cbr\u003e\u003cstrong\u003e\u003cspan dir=\"auto\"\u003eMetabolism\u003c\/span\u003e\u003c\/strong\u003e\u003cbr\u003e\u003cspan dir=\"auto\"\u003eMeloxicam is found mainly in plasma and is also a product predominantly excreted in the bile, while only traces of the basic active substance are found in the urine. Meloxicam is metabolized with the production of an alcohol, an acid derivative and several polar metabolites. All important metabolites have been shown to be pharmacologically inactive.\u003c\/span\u003e\u003cbr\u003e\u003cstrong\u003e\u003cspan dir=\"auto\"\u003eElimination\u003c\/span\u003e\u003c\/strong\u003e\u003cbr\u003e\u003cspan dir=\"auto\"\u003eMeloxicam is eliminated with a half-life of 24 hours. Approximately 75% of the administered dose is eliminated in the faeces, the remainder being eliminated in the urine.\u003c\/span\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003e\u003cspan dir=\"auto\"\u003ePHARMACEUTICAL PARTICULARS\u003c\/span\u003e\u003c\/strong\u003e\u003cbr\u003e\u003cspan dir=\"auto\"\u003eList of excipients: Sodium saccharinate; Sodium carboxymethyl cellulose; Colloidal silicon dioxide; Citric acid monohydrate; Sorbitol solution; Disodium hydrogen phosphate dodecahydrate; Sodium benzoate; Honey flavor.\u003c\/span\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003e\u003cspan dir=\"auto\"\u003eIncompatibilities\u003c\/span\u003e\u003c\/strong\u003e\u003cspan dir=\"auto\"\u003e\u003cspan\u003e \u003c\/span\u003eNone known.\u003c\/span\u003e\u003c\/p\u003e\n\u003c\/div\u003e","brand":"Chanelle","offers":[{"title":"Default Title","offer_id":53020431745371,"sku":null,"price":56.99,"currency_code":"EUR","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0476\/3261\/3543\/files\/rheumocam-solutie-orala-caine-1-5-mg-ml-42-ml_100067158.webp?v=1779186155","url":"https:\/\/www.petshopluna.com\/it\/products\/rheumocam-1-5mg-ml-42-ml-meloxicam-dogs","provider":"Pet Shop Maya","version":"1.0","type":"link"}