{"product_id":"vominil-10-mg-ml-25-ml-maropitant-10-mg-dogs-and-cats-cani-e-gatti","title":"VOMINIL 10 MG\/ML 25 ML \/\/ Maropitant 10 mg \/\/ dogs and cats \/ cani e gatti","description":"\u003cdiv class=\"product_section product_section_description\"\u003e\n\u003cdiv class=\"product_section_content\"\u003e\n\u003cdiv class=\"__i\"\u003e\n\u003cdiv class=\"description\"\u003e\n\u003cp\u003e\u003cspan\u003e\u003cstrong\u003eINJECTABLE SOLUTION FOR DOGS AND CATS VOMINIL 10MG\/ML 25ML\u003c\/strong\u003e\u003c\/span\u003e\u003cbr\u003e\u003cbr\u003e\u003cspan\u003eVominil 10 mg\/ml injectable solution for dogs and cats.\u003c\/span\u003e\u003cbr\u003e\u003cbr\u003e\u003cstrong\u003e\u003cspan\u003eCOMPOSITION:\u003c\/span\u003e\u003c\/strong\u003e\u003cbr\u003e\u003cspan\u003eEach ml contains:\u003c\/span\u003e\u003cbr\u003e\u003cstrong\u003e\u003cspan\u003eActive substance:\u003c\/span\u003e\u003c\/strong\u003e\u003cbr\u003e\u003cspan\u003eMaropitant 10 mg\u003cbr\u003e(as maropitant citrate monohydrate)\u003c\/span\u003e\u003cbr\u003e\u003cstrong\u003e\u003cspan\u003eExcipients:\u003c\/span\u003e\u003c\/strong\u003e\u003cbr\u003e\u003cspan\u003en-Butanol 22 mg\u003c\/span\u003e\u003cbr\u003e\u003cspan\u003eClear, colourless to almost colourless solution for injection.\u003c\/span\u003e\u003cbr\u003e\u003cbr\u003e\u003cstrong\u003e\u003cspan\u003eTARGET SPECIES:\u003c\/span\u003e\u003c\/strong\u003e\u003cbr\u003e\u003cspan\u003eDogs and cats.\u003c\/span\u003e\u003cbr\u003e\u003cbr\u003e\u003cstrong\u003e\u003cspan\u003eINSTRUCTIONS FOR USE:\u003c\/span\u003e\u003c\/strong\u003e\u003cbr\u003e\u003cstrong\u003e\u003cu\u003eDogs:\u003c\/u\u003e\u003c\/strong\u003e\u003cspan\u003e\u003cbr\u003eFor the treatment and prevention of nausea induced by chemotherapy.\u003c\/span\u003e\u003cspan\u003e\u003cbr\u003eFor the prevention of vomiting, except that induced by motion sickness.\u003c\/span\u003e\u003cspan\u003e\u003cbr\u003eFor the treatment of vomiting in combination with other supportive measures.\u003c\/span\u003e\u003cspan\u003e\u003cbr\u003eFor the prevention of nausea and vomiting in the perioperative period and to improve recovery from general anaesthesia after the use of morphine, an opioid agonist of the µ-receptor.\u003c\/span\u003e\u003cspan\u003e\u003c\/span\u003e\u003cspan\u003e\u003cbr\u003e\u003cstrong\u003e\u003cu\u003eCats:\u003c\/u\u003e\u003c\/strong\u003e\u003c\/span\u003e\u003cspan\u003e\u003cbr\u003eFor the prevention of vomiting and the reduction of nausea, except that induced by motion sickness.\u003c\/span\u003e\u003cspan\u003e\u003cbr\u003eFor the treatment of vomiting in combination with other supportive measures.\u003c\/span\u003e\u003cstrong\u003e\u003cspan\u003e\u003cbr\u003e\u003cbr\u003eCONTRAINDICATIONS:\u003c\/span\u003e\u003c\/strong\u003e\u003cspan\u003e\u003cbr\u003eDo not use in cases of hypersensitivity to the active substance or to any of the excipients.\u003c\/span\u003e\u003cstrong\u003e\u003cspan\u003e\u003cbr\u003e\u003cbr\u003eSPECIAL WARNINGS:\u003c\/span\u003e\u003c\/strong\u003e\u003cspan\u003e\u003cbr\u003e\u003cstrong\u003e\u003cu\u003eSpecial warnings:\u003c\/u\u003e\u003c\/strong\u003e\u003c\/span\u003e\u003cspan\u003e\u003cbr\u003eVomiting may be associated with serious, severely debilitating conditions, including gastrointestinal obstruction, therefore appropriate diagnostic evaluations should be performed.\u003c\/span\u003e\u003cbr\u003e\u003cspan\u003eGood veterinary practice recommends that antiemetics be used in combination with other veterinary and supportive measures, such as dietary control and rehydration therapy, while addressing the underlying causes of vomiting.\u003c\/span\u003e\u003cspan\u003e\u003cbr\u003eThe veterinary medicinal product is not recommended for use against vomiting due to motion sickness.\u003c\/span\u003e\u003cbr\u003e\u003cstrong\u003e\u003cspan\u003eDogs:\u003c\/span\u003e\u003c\/strong\u003e\u003cbr\u003e\u003cspan\u003eAlthough maropitant has been shown to be effective in both the treatment and prevention of chemotherapy-induced emesis, it has been shown to be more effective when used preventively. For this reason, it is recommended to administer the antiemetic before administering the chemotherapeutic agent.\u003c\/span\u003e\u003cspan\u003e\u003c\/span\u003e\u003cspan\u003e\u003cbr\u003e\u003cstrong\u003eCats:\u003c\/strong\u003e\u003c\/span\u003e\u003cspan\u003e\u003cbr\u003eThe efficacy of maropitant in reducing nausea has been demonstrated in studies using a model (xylazine-induced nausea).\u003c\/span\u003e\u003cbr\u003e\u003cbr\u003e\u003cstrong\u003e\u003cu\u003eSpecial precautions for safe use in the target species:\u003c\/u\u003e\u003c\/strong\u003e\u003cspan\u003e\u003cbr\u003eThe safety of the veterinary medicinal product has not been established in dogs less than 8 weeks of age or in cats less than 16 weeks of age and in pregnant or lactating bitches or cats.\u003cbr\u003eUse only according to the benefit-risk assessment by the responsible veterinarian.\u003c\/span\u003e\u003cbr\u003e\u003cspan\u003e\u003c\/span\u003e\u003cspan\u003eMaropitant is metabolised in the liver and should therefore be used with caution in patients with liver disease. As maropitant accumulates in the body during the 14-day treatment period due to metabolic saturation, close monitoring of liver function and any adverse events should be implemented during long-term treatment. The veterinary medicinal product should be used with caution in animals suffering from\/predisposed to cardiac disease, as maropitant has affinity for \u003c\/span\u003e\u003cspan\u003e\u003cstrong\u003eCa\u003c\/strong\u003e  and \u003cstrong\u003eK\u003c\/strong\u003e\u003c\/span\u003e\u003cbr\u003e\u003cspan\u003eion channels. An increase of approximately 10% in the QT interval of the ECG was observed in a study in healthy Beagle dogs administered 8 mg\/kg orally, however, such an increase is unlikely to be of clinical significance. \u003cstrong\u003e\u003c\/strong\u003e\u003cstrong\u003e\u003c\/strong\u003e\u003c\/span\u003e\u003cspan\u003e\u003c\/span\u003e\u003cspan\u003eDue to the frequent occurrence of transient pain during subcutaneous injection, appropriate animal restraint measures should be applied. Injecting the veterinary medicinal product at refrigerated temperature may reduce pain on injection.\u003c\/span\u003e\u003cspan\u003e\u003cbr\u003e\u003cbr\u003e\u003cstrong\u003e\u003cu\u003eSpecial precautions to be taken by the person administering the veterinary medicinal product to animals:\u003c\/u\u003e\u003c\/strong\u003e\u003c\/span\u003e\u003cspan\u003e\u003cbr\u003eThis product may cause skin sensitization. People with known hypersensitivity to maropitant should administer the veterinary medicinal product with caution. Wash the skin immediately after exposure with large amounts of water. If symptoms such as a rash occur following accidental exposure, seek medical advice and show the doctor this warning.\u003c\/span\u003e\u003cbr\u003e\u003cspan\u003eThis veterinary medicinal product may be irritating to the eyes. Avoid contact with eyes. In case of accidental contact of the product with eyes, rinse with large amounts of fresh water. If symptoms occur, seek medical advice.\u003c\/span\u003e\u003cspan\u003e\u003cbr\u003eMaropitant is a neurokinin-1 (NK.1) receptor antagonist that acts on the central nervous system. Accidental self-injection or ingestion may result in nausea, dizziness and drowsiness. Care should be taken to avoid accidental self-injection. In case of accidental self-injection or ingestion, seek medical advice immediately and show the package leaflet or the label to the physician.  \u003c\/span\u003e\u003cspan\u003eWash hands after use.\u003cbr\u003e\u003cbr\u003e\u003cstrong\u003e\u003cu\u003ePregnancy and lactation:\u003c\/u\u003e\u003c\/strong\u003e\u003c\/span\u003e\u003cspan\u003e\u003cbr\u003eUse only according to the benefit-risk assessment by the responsible veterinarian as no conclusive reproductive toxicity studies have been performed in any animal species.\u003c\/span\u003e\u003cu\u003e\u003cspan\u003e\u003cbr\u003e\u003cbr\u003eI\u003cstrong\u003enteraction with other medicinal products and other forms of interaction\u003c\/strong\u003e: \u003c\/span\u003e\u003c\/u\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cu\u003e\u003cspan\u003eThe veterinary medicinal product should not be used concomitantly with \u003c\/span\u003e\u003c\/u\u003e\u003cspan\u003e\u003cstrong\u003eCa\u003c\/strong\u003e\u003c\/span\u003e\u003cspan\u003e\u003cbr\u003echannel antagonists as maropitant has affinity for \u003cstrong\u003eCa\u003c\/strong\u003e channels .\u003cstrong\u003e\u003c\/strong\u003e\u003cstrong\u003e\u003c\/strong\u003e\u003c\/span\u003e\u003cspan\u003e\u003cbr\u003eMaropitant is highly bound to plasma proteins and may compete with other highly bound medicinal products.\u003c\/span\u003e\u003cbr\u003e\u003cbr\u003e\u003cstrong\u003e\u003cu\u003eOverdose: \u003c\/u\u003e\u003c\/strong\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cspan\u003eApart from transient injection site reactions following subcutaneous administration, maropitant was well tolerated in young dogs and cats injected daily at doses up to 5 mg\/kg (5 times the recommended dose) for 15 consecutive days (3 times the recommended duration of administration). No data on overdose in adult cats are available. \u003c\/span\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cspan\u003e\u003cu\u003e\u003cstrong\u003eMajor incompatibilities\u003c\/strong\u003e:\u003c\/u\u003e \u003c\/span\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cspan\u003eIn the absence of compatibility studies, this veterinary medicinal product should not be mixed with other veterinary medicinal products in the same syringe. \u003c\/span\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003e\u003cu\u003eAdverse events:\u003c\/u\u003e \u003c\/strong\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cspan\u003eDogs and cats:\u003c\/span\u003e\u003cspan\u003e\u003cbr\u003e\u003c\/span\u003e\u003cspan\u003eVery common (\u0026gt; 1 animal\/10 animals treated): pain \u003c\/span\u003e\u003cspan\u003eat the injection site*.\u003c\/span\u003e\u003cspan\u003e\u003cbr\u003eVery rare (\u0026lt; 1 animal\/10,000 animals treated, including isolated reports): \u003c\/span\u003e\u003cspan\u003eanaphylactic-type reaction, allergic oedema, urticaria, erythema, collapse, dyspnoea, pale mucous membranes, lethargy, neurological disorders (e.g. ataxia, convulsions, seizures, muscle tremors).\u003c\/span\u003e\u003cspan\u003e\u003c\/span\u003e\u003cspan\u003e\u003cbr\u003e*May occur when injected subcutaneously. Moderate to severe injection reactions are observed in approximately one third of cats.\u003c\/span\u003e\u003cspan\u003e\u003cbr\u003e\u003cbr\u003eReporting of adverse events is important. It allows for continued monitoring of the safety of a veterinary medicinal product. If you notice any side effects, even those not already listed in this leaflet, or you think that the medicine has not had an effect, please contact your veterinary surgeon first. You can also report adverse events to the Marketing Authorisation Holder or the local representative of the Marketing Authorisation Holder using the contact details at the end of this leaflet or via the national reporting system: \u003c\/span\u003e\u003ca\u003e\u003cspan\u003efannacovigilenta@ansvsa.ro, icbmv@icbmv.ro.\u003c\/span\u003e\u003c\/a\u003e\u003c\/p\u003e\n\u003cp\u003e\u003ca\u003e\u003cspan\u003e \u003c\/span\u003e\u003c\/a\u003e\u003cstrong\u003e\u003cu\u003eDosage for each species, routes of administration and methods of administration:\u003c\/u\u003e \u003c\/strong\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cspan\u003eFor subcutaneous or intravenous use. The veterinary medicinal product should be injected subcutaneously or intravenously, once daily, at a dose of 1 mg\/kg body weight (1 ml\/10 kg body weight) for up to 5 consecutive days.  Intravenous administration of the veterinary medicinal product should be carried out in a single bolus without mixing the veterinary medicinal product with any other fluids. In order to ensure the correct dose, body weight should be determined as accurately as possible. The rubber stopper can be safely punctured up to 100 times.\u003cu\u003e \u003c\/u\u003e\u003c\/span\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003e\u003cu\u003eRecommendations for correct administration: \u003c\/u\u003e\u003c\/strong\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cspan\u003eTo prevent vomiting, the veterinary medicinal product should be administered more than 1 hour in advance. The duration of effect is approximately 24 hours and, for this reason, treatment may be given the night before administration of an agent that may cause emesis, e.g. chemotherapy. Since the pharmacokinetic variation is large and maropitant accumulates in the body after repeated daily administration, lower doses than those recommended may be sufficient for some individuals even when the dose is repeated. For subcutaneous injection, see also “Special precautions for safe use in target species”. \u003c\/span\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cspan\u003e\u003cstrong\u003eWITHDRAWAL PERIODS:\u003c\/strong\u003e\u003c\/span\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cspan\u003e Not applicable. \u003c\/span\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cspan\u003e\u003cu\u003e\u003cstrong\u003eSpecial precautions for storage\u003c\/strong\u003e:\u003c\/u\u003e \u003c\/span\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cspan\u003eKeep out of the sight and reach of children. Do not freeze. Do not use this veterinary medicinal product after the expiry date which is stated on the label and carton. The expiry date refers to the last day of that month. Shelf life after first opening the immediate packaging: 28 days.\u003c\/span\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003e \u003cu\u003eSpecial precautions for disposal:\u003c\/u\u003e\u003c\/strong\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cspan\u003e Medicines should not be disposed of via wastewater or household waste.\u003c\/span\u003e\u003cspan\u003e\u003c\/span\u003e\u003cspan\u003e\u003cbr\u003e\u003c\/span\u003e\u003cspan\u003eUse the return systems for unused veterinary medicinal products or waste materials derived from such products, in accordance with local requirements and national applicable collection systems. These measures should help protect the environment.\u003c\/span\u003e\u003cbr\u003e\u003cspan\u003eAsk your veterinarian or pharmacist for information on how to dispose of medicines no longer required.\u003c\/span\u003e\u003cspan\u003e\u003cbr\u003e\u003cbr\u003e\u003cstrong\u003e\u003cu\u003eClassification of veterinary medicinal products:\u003c\/u\u003e\u003c\/strong\u003e\u003c\/span\u003e\u003cspan\u003e\u003cbr\u003eVeterinary medicinal product subject to prescription.\u003cbr\u003e\u003cbr\u003e\u003cstrong\u003eSIZE:\u003c\/strong\u003e\u003c\/span\u003e\u003cbr\u003e\u003cspan\u003ebottle x 25 ml.\u003c\/span\u003e\u003c\/p\u003e\n\u003c\/div\u003e\n\u003c\/div\u003e\n\u003c\/div\u003e\n\u003c\/div\u003e\n\u003cp\u003e \u003c\/p\u003e\n\u003cp\u003e \u003c\/p\u003e\n\u003cp\u003e \u003c\/p\u003e\n\u003cp\u003e \u003c\/p\u003e\n\u003cp\u003e\u003cspan\u003e\u003cstrong\u003eSOLUZIONE INIETTABILE PER CANI E GATTI VOMINIL 10MG\/ML 25ML\u003c\/strong\u003e\u003c\/span\u003e\u003cbr\u003e\u003cbr\u003e\u003cspan\u003eVominil 10 mg\/ml soluzione iniettabile per cani e gatti.\u003c\/span\u003e\u003cbr\u003e\u003cbr\u003e\u003cstrong\u003e\u003cspan\u003eCOMPOSIZIONE:\u003c\/span\u003e\u003c\/strong\u003e\u003cbr\u003e\u003cspan\u003eOgni ml contiene:\u003c\/span\u003e\u003cbr\u003e\u003cstrong\u003e\u003cspan\u003ePrincipio attivo:\u003c\/span\u003e\u003c\/strong\u003e\u003cbr\u003e\u003cspan\u003eMaropitant 10 mg\u003cbr\u003e(come maropitant citrato monoidrato)\u003c\/span\u003e\u003cbr\u003e\u003cstrong\u003e\u003cspan\u003eEccipienti:\u003c\/span\u003e\u003c\/strong\u003e\u003cbr\u003e\u003cspan\u003en-butanolo 22 mg\u003c\/span\u003e\u003cbr\u003e\u003cspan\u003eSoluzione iniettabile limpida, incolore o quasi incolore.\u003c\/span\u003e\u003cbr\u003e\u003cbr\u003e\u003cstrong\u003e\u003cspan\u003eSPECIE DESTINATARI:\u003c\/span\u003e\u003c\/strong\u003e\u003cbr\u003e\u003cspan\u003eCani e gatti.\u003c\/span\u003e\u003cbr\u003e\u003cbr\u003e\u003cstrong\u003e\u003cspan\u003eISTRUZIONI PER L'USO:\u003c\/span\u003e\u003c\/strong\u003e\u003cbr\u003e\u003cstrong\u003e\u003cu\u003eCani:\u003c\/u\u003e\u003c\/strong\u003e\u003cspan\u003e\u003cbr\u003eper il trattamento e la prevenzione della nausea indotta dalla chemioterapia.\u003c\/span\u003e\u003cspan\u003e\u003cbr\u003ePer la prevenzione del vomito, eccetto quello indotto dalla cinetosi.\u003c\/span\u003e\u003cspan\u003e\u003cbr\u003ePer il trattamento del vomito in combinazione con altre misure di supporto.\u003c\/span\u003e\u003cspan\u003e\u003cbr\u003ePer la prevenzione della nausea e del vomito nel periodo perioperatorio e per migliorare il risveglio dall'anestesia generale dopo l'uso di morfina, un agonista del recettore µ degli oppioidi.\u003c\/span\u003e\u003cspan\u003e\u003c\/span\u003e\u003cspan\u003e\u003cbr\u003e\u003cstrong\u003e\u003cu\u003eGatti:\u003c\/u\u003e\u003c\/strong\u003e\u003c\/span\u003e\u003cspan\u003e\u003cbr\u003eper la prevenzione del vomito e la riduzione della nausea, eccetto quella indotta dalla cinetosi.\u003c\/span\u003e\u003cspan\u003e\u003cbr\u003ePer il trattamento del vomito in combinazione con altre misure di supporto.\u003c\/span\u003e\u003cstrong\u003e\u003cspan\u003e\u003cbr\u003e\u003cbr\u003eCONTROINDICAZIONI:\u003c\/span\u003e\u003c\/strong\u003e\u003cspan\u003e\u003cbr\u003eNon usare in caso di ipersensibilità al principio attivo o ad uno qualsiasi degli eccipienti.\u003c\/span\u003e\u003cstrong\u003e\u003cspan\u003e\u003cbr\u003e\u003cbr\u003eAVVERTENZE SPECIALI:\u003c\/span\u003e\u003c\/strong\u003e\u003cspan\u003e\u003cbr\u003e\u003cstrong\u003e\u003cu\u003eAvvertenze speciali:\u003c\/u\u003e\u003c\/strong\u003e\u003c\/span\u003e\u003cspan\u003e\u003cbr\u003eIl vomito può essere associato a condizioni gravi e fortemente debilitanti, tra cui l'ostruzione gastrointestinale, pertanto devono essere eseguite opportune valutazioni diagnostiche.\u003c\/span\u003e\u003cbr\u003e\u003cspan\u003eLe buone pratiche veterinarie raccomandano di utilizzare gli antiemetici in combinazione con altre misure veterinarie e di supporto, come il controllo della dieta e la terapia reidratante, affrontando anche le cause sottostanti il ​​vomito.\u003c\/span\u003e\u003cspan\u003e\u003cbr\u003eIl medicinale veterinario non è raccomandato per l'uso contro il vomito causato dalla cinetosi.\u003c\/span\u003e\u003cbr\u003e\u003cstrong\u003e\u003cspan\u003eCani:\u003c\/span\u003e\u003c\/strong\u003e\u003cbr\u003e\u003cspan\u003eSebbene sia stato dimostrato che il maropitant è efficace sia per il trattamento che per la prevenzione dell'emesi indotta dalla chemioterapia, è stato osservato che è molto più efficace se usato a scopo preventivo. Per questo motivo si raccomanda di somministrare l'antiemetico prima di somministrare il chemioterapico.\u003c\/span\u003e\u003cspan\u003e\u003c\/span\u003e\u003cspan\u003e\u003cbr\u003e\u003cstrong\u003eGatti:\u003c\/strong\u003e\u003c\/span\u003e\u003cspan\u003e\u003cbr\u003el'efficacia del maropitant nel ridurre la nausea è stata dimostrata in studi che utilizzavano un modello (nausea indotta da xilazina).\u003c\/span\u003e\u003cbr\u003e\u003cbr\u003e\u003cstrong\u003e\u003cu\u003ePrecauzioni speciali per un impiego sicuro nelle specie di destinazione:\u003c\/u\u003e\u003c\/strong\u003e\u003cspan\u003e\u003cbr\u003ela sicurezza del medicinale veterinario non è stata stabilita nei cani di età inferiore a 8 settimane o nei gatti di età inferiore a 16 settimane e nelle cagne o gatte gravide o in allattamento.\u003cbr\u003eUtilizzare solo conformemente alla valutazione del rapporto beneficio-rischio del veterinario responsabile.\u003c\/span\u003e\u003cbr\u003e\u003cspan\u003e\u003c\/span\u003e\u003cspan\u003eIl maropitant viene metabolizzato nel fegato e per questo motivo deve essere usato con cautela nei pazienti affetti da malattie epatiche. Poiché il maropitant si accumula nell'organismo durante il periodo di trattamento di 14 giorni a causa della saturazione metabolica, durante il trattamento a lungo termine è necessario monitorare attentamente la funzionalità epatica e gli eventuali eventi avversi.\u003c\/span\u003e\u003cbr\u003e\u003cspan\u003eIl medicinale veterinario deve essere usato con cautela negli animali affetti da\/predisposti a cardiopatia, poiché il maropitant ha affinità per i canali ionici \u003cstrong\u003eCa\u003c\/strong\u003e  e \u003cstrong\u003eK.\u003c\/strong\u003e Un aumento di circa il 10% nell'intervallo QT dell'ECG è stato osservato in uno studio su cani Beagle sani a cui sono stati somministrati 8 mg\/kg per via orale, tuttavia, è improbabile che tale aumento abbia rilevanza clinica. \u003c\/span\u003e\u003cspan\u003e\u003c\/span\u003e\u003cspan\u003eA causa della frequente comparsa di dolore transitorio durante l'iniezione sottocutanea, devono essere adottate misure idonee di contenimento dell'animale. L'iniezione del medicinale veterinario a temperatura refrigerata può ridurre il dolore al momento dell'iniezione.\u003c\/span\u003e\u003cspan\u003e\u003cbr\u003e\u003cbr\u003e\u003cu\u003e\u003cstrong\u003ePrecauzioni speciali che devono essere adottate dalla persona che somministra il medicinale veterinario agli animali\u003c\/strong\u003e:\u003c\/u\u003e\u003c\/span\u003e\u003cspan\u003e\u003cbr\u003eQuesto prodotto può causare sensibilizzazione cutanea. Le persone con nota ipersensibilità al maropitant devono somministrare il medicinale veterinario con cautela. Dopo l'esposizione, lavare immediatamente la pelle con abbondante acqua. Se dopo un'esposizione accidentale si manifestano sintomi come eruzione cutanea, consultare un medico e mostrargli questa avvertenza.\u003c\/span\u003e\u003cbr\u003e\u003cspan\u003eQuesto medicinale veterinario può essere irritante per gli occhi. Evitare il contatto con gli occhi. In caso di contatto accidentale del prodotto con gli occhi, sciacquare abbondantemente con acqua fresca. Se si manifestano sintomi, consultare un medico.\u003c\/span\u003e\u003cspan\u003e\u003cbr\u003eIl maropitant è un antagonista del recettore della neurochinina-1 (NK.1) che agisce sul sistema nervoso centrale. L'autoiniezione o l'ingestione accidentale possono provocare nausea, vertigini e sonnolenza. Bisogna fare attenzione a non autoiniettarsi accidentalmente. In caso di autoiniezione o ingestione accidentale, consultare immediatamente un medico mostrandogli il foglietto illustrativo o l'etichetta.  \u003c\/span\u003e\u003cspan\u003eLavarsi le mani dopo l'uso.\u003cbr\u003e\u003cbr\u003e\u003cstrong\u003e\u003cu\u003eGravidanza e allattamento:\u003c\/u\u003e\u003c\/strong\u003e\u003c\/span\u003e\u003cspan\u003e\u003cbr\u003eusare solo conformemente alla valutazione del rapporto beneficio-rischio del veterinario responsabile, poiché non sono stati condotti studi conclusivi sulla tossicità riproduttiva in nessuna specie animale.\u003c\/span\u003e\u003cu\u003e\u003cspan\u003e\u003cbr\u003e\u003cbr\u003e\u003cstrong\u003eInterazione con altri medicinali ed altre forme di interazione\u003c\/strong\u003e:\u003c\/span\u003e\u003c\/u\u003e\u003cspan\u003e\u003cbr\u003eil medicinale veterinario non deve essere usato contemporaneamente agli antagonisti dei canali \u003cstrong\u003edel Ca\u003c\/strong\u003e perché il maropitant ha affinità per i canali del \u003cstrong\u003eCa.\u003c\/strong\u003e\u003c\/span\u003e\u003cspan\u003e\u003cbr\u003eIl maropitant è fortemente legato alle proteine ​​plasmatiche e può competere con altri farmaci fortemente legati.\u003c\/span\u003e\u003cbr\u003e\u003cbr\u003e\u003cstrong\u003e\u003cu\u003eSovradosaggio: \u003c\/u\u003e\u003c\/strong\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cspan\u003ea parte le reazioni transitorie nel sito di iniezione a seguito di somministrazione sottocutanea, il maropitant è stato ben tollerato nei cani e nei gatti giovani ai quali è stata somministrata una dose giornaliera fino a 5 mg\/kg (5 volte la dose raccomandata) per 15 giorni consecutivi (3 volte la durata di somministrazione raccomandata). Non sono disponibili dati sul sovradosaggio nei gatti adulti.\u003c\/span\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cspan\u003e\u003cstrong\u003e \u003cu\u003eIncompatibilità principali:\u003c\/u\u003e\u003c\/strong\u003e\u003c\/span\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cspan\u003e in assenza di studi di compatibilità, questo medicinale veterinario non deve essere miscelato con altri medicinali veterinari nella stessa siringa.\u003c\/span\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cspan\u003e \u003cu\u003eEventi avversi:\u003c\/u\u003e Cani e gatti:\u003c\/span\u003e\u003cspan\u003e\u003cbr\u003e\u003c\/span\u003e\u003cspan\u003e\u003cbr\u003e\u003c\/span\u003e\u003cspan\u003e\u003c\/span\u003e\u003cspan\u003eMolto comune (\u0026gt; 1 animale\/10 animali trattati): dolore \u003c\/span\u003e\u003cspan\u003enel sito di iniezione*.\u003c\/span\u003e\u003cspan\u003e\u003cbr\u003eMolto raro (\u0026lt;1 animale\/10.000 animali trattati, comprese segnalazioni isolate): \u003c\/span\u003e\u003cspan\u003ereazione di tipo anafilattico, edema allergico, orticaria, eritema, collasso, dispnea, pallore delle mucose, letargia, disturbi neurologici (ad es. atassia, convulsioni, crisi epilettiche, tremore muscolare).\u003c\/span\u003e\u003cspan\u003e\u003c\/span\u003e\u003cspan\u003e\u003cbr\u003e*Può verificarsi in caso di iniezione sottocutanea. In circa un terzo dei gatti si osservano reazioni da moderate a gravi all'iniezione.\u003c\/span\u003e\u003cspan\u003e\u003cbr\u003e\u003cbr\u003eSegnalare gli eventi avversi è importante. Consente il monitoraggio continuo della sicurezza di un medicinale veterinario. Se si notano effetti collaterali, anche se non elencati in questo foglio illustrativo, o si ritiene che il medicinale non abbia avuto effetto, contattare prima il veterinario. È inoltre possibile segnalare gli effetti indesiderati al titolare dell'autorizzazione all'immissione in commercio o al rappresentante locale del titolare dell'autorizzazione all'immissione in commercio, utilizzando i recapiti indicati alla fine di questo foglio illustrativo o tramite il sistema nazionale di segnalazione: \u003c\/span\u003e\u003ca\u003e\u003cspan\u003efannacovigilenta@ansvsa.ro, icbmv@icbmv.ro.\u003c\/span\u003e\u003c\/a\u003e\u003c\/p\u003e\n\u003cp\u003e\u003ca\u003e\u003cspan\u003e \u003c\/span\u003e\u003c\/a\u003e\u003cspan\u003e\u003cstrong\u003e\u003cu\u003eDosaggi per ciascuna specie, vie di somministrazione e metodi di somministrazione:\u003c\/u\u003e \u003c\/strong\u003e\u003c\/span\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cspan\u003e\u003cstrong\u003ePer uso sottocutaneo o endovenoso\u003c\/strong\u003e.\u003c\/span\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cspan\u003e Il medicinale veterinario deve essere iniettato per via sottocutanea o endovenosa, una volta al giorno, alla dose di 1 mg\/kg di peso corporeo (1 ml\/10 kg di peso corporeo) per un massimo di 5 giorni consecutivi.  La somministrazione endovenosa del medicinale veterinario deve essere effettuata in un unico bolo, senza miscelare il medicinale veterinario con altri liquidi. Per garantire la dose corretta, il peso corporeo deve essere determinato nel modo più accurato possibile. Il tappo di gomma può essere forato in tutta sicurezza fino a 100 volte.\u003cu\u003e \u003c\/u\u003e\u003c\/span\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cspan\u003e\u003cu\u003e\u003cstrong\u003eRaccomandazioni per una corretta somministrazione:\u003c\/strong\u003e \u003c\/u\u003e\u003c\/span\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cspan\u003eper prevenire il vomito, il medicinale veterinario deve essere somministrato con più di 1 ora di anticipo. La durata dell'effetto è di circa 24 ore e per questo motivo il trattamento può essere effettuato la sera prima della somministrazione di un agente che può provocare vomito, ad esempio la chemioterapia. Poiché la variazione farmacocinetica è ampia e il maropitant si accumula nell'organismo dopo somministrazioni giornaliere ripetute, per alcuni individui possono essere sufficienti dosi inferiori a quelle raccomandate, anche quando la somministrazione viene ripetuta. Per l'iniezione sottocutanea, vedere anche \"Precauzioni speciali per l'impiego sicuro nelle specie di destinazione\".\u003c\/span\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cspan\u003e \u003cstrong\u003ePERIODI DI ATTESA:\u003c\/strong\u003e Non applicabile. \u003c\/span\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cspan\u003e\u003cu\u003e\u003cstrong\u003ePrecauzioni speciali per la conservazione\u003c\/strong\u003e:\u003c\/u\u003e \u003c\/span\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cspan\u003eTenere fuori dalla vista e dalla portata dei bambini. Non congelare. Non usare questo medicinale veterinario dopo la data di scadenza riportata sull'etichetta e sulla scatola. La data di scadenza si riferisce all'ultimo giorno di quel mese. Periodo di validità dopo la prima apertura del confezionamento primario: 28 giorni.\u003c\/span\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cspan\u003e\u003cstrong\u003e \u003c\/strong\u003e\u003cu\u003e\u003cstrong\u003ePrecauzioni speciali per lo smaltimento\u003c\/strong\u003e:\u003c\/u\u003e \u003c\/span\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cspan\u003eI medicinali non devono essere smaltiti nelle acque reflue o nei rifiuti domestici.\u003c\/span\u003e\u003cspan\u003e\u003c\/span\u003e\u003cspan\u003e\u003cbr\u003e\u003c\/span\u003e\u003cspan\u003e\u003c\/span\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cspan\u003eUtilizzare sistemi per il riciclaggio dei medicinali veterinari inutilizzati o dei materiali di scarto derivati ​​da tali prodotti, in conformità con i requisiti locali e i sistemi di raccolta nazionali applicabili. Tali misure dovrebbero contribuire alla tutela dell'ambiente.\u003c\/span\u003e\u003cbr\u003e\u003cspan\u003eChiedi al tuo veterinario o al farmacista informazioni su come smaltire i medicinali che non utilizzi più.\u003c\/span\u003e\u003cspan\u003e\u003cbr\u003e\u003cbr\u003e\u003cstrong\u003e\u003cu\u003eClassificazione dei medicinali veterinari:\u003c\/u\u003e\u003c\/strong\u003e\u003c\/span\u003e\u003cspan\u003e\u003cbr\u003eMedicinale veterinario disponibile dietro prescrizione medica.\u003cbr\u003e\u003cbr\u003e\u003cstrong\u003eFORMATO:\u003c\/strong\u003e\u003c\/span\u003e\u003cbr\u003e\u003cspan\u003eflacone x 25 ml.\u003c\/span\u003e\u003c\/p\u003e","brand":"Vet Viva","offers":[{"title":"Default Title","offer_id":50192083255643,"sku":"","price":124.99,"currency_code":"EUR","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0476\/3261\/3543\/files\/13234614_product.jpg?v=1741276872","url":"https:\/\/www.petshopluna.com\/en-at\/products\/vominil-10-mg-ml-25-ml-maropitant-10-mg-dogs-and-cats-cani-e-gatti","provider":"Pet Shop Maya","version":"1.0","type":"link"}